The trick, then, would be to Path of exile currency discount items that your character can not use or are of reduced value. Item rarity is indicated by colours: White: Normal, Blue: Magic, Yellow: Rare,Orange: Unique.

You can pretty much discount white items unless you're going to go back to town and have the room to spare for them. Rarer items are usually worth picking up and promoting, even if you have to hold onto them for a short time. And needless to say, any item that appears better than your current equipment is well worth catching -- even in the event that you have to lose something else temporarily as you equip it.

By default, figures do not regenerate life however they do regenerate a tiny amount of mana every second. You can manually synchronize life and mana by using the appropriate type of flask. Flask charges automatically refill when visiting a town or hideout. They also profit charges from killing enemies. Equipping better flasks increases the amount of daily life or mana regained, and can have other effects as well.

Gear and passive abilities can boost regeneration for either stat or even steal life and mana from hits and kills. At bare minimum, you want to buy poe orbs have some life regeneration so it is possible to regain health between conflicts.